Apoptotic effect of reduced Graphene Oxide on MCF-7 Breast cancer cell line using Asparagus Racemosus roots

Abstract

In the modern era, the major health issue is cancer. Cancer is one of the second- deadliest death-causing diseases worldwide. Graphene is a carbon-based material that has drawn a great deal of attention because of its eccentric chemical and physical properties. Moreover, graphene can be transformed into graphene oxide or reduced graphene oxide, depending on its application. Chemical reduction of graphene oxide was associated with toxic and harmful reducing compounds; hence, the green, efficient and cost-effective approach for graphene synthesis is using plant extract. In this contemporary study, the reduced graphene oxide can be synthesized from Asparagus racemosus root extract, involving anti-cancer activity. The reduced graphene oxide was characterized from UV-Visible, FT-IR, SEM and XRD. The size and shape of the synthesized reduced graphene oxide were confirmed from SEM studies. The anti-cancer activity showed a strong cytotoxic effect on the tested cell line.