Abstract
OBJECTIVE: Cleavage stage embryo biopsy makes embryos more vulnerable to development failure. Cryopreserved biopsied embryos are at a higher risk for developmental or implantation failure. The aim of our study was to 1) examine if apoptosis is induced in cleavage stage embryos after biopsy and 2) evaluate the extent of apoptosis following vitrification or slow cryopreservation of biopsied cleavage stage embryos.
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