Abstract

The emergency treatment of most ingestion problems involves gastric lavage or induction of emesis. Forceful emesis, superior to lavage, is usually induced by syrup of ipecac. A more rapid, efficient and controlled method utilizing apomorphine hydrochloride and a narcotic antagonist has not been popular because of difficulties in determining dosage in addition to the problems raised by the depressant properties of both the apomorphine and its antagonists. The absence of depressant effects with the newer antagonist, naloxone hydrochloride, renders it safer for use in terminating emesis induced by apomorphine. A dose calculated schedule, based on a level of 0.066 mg/kg for apomorphine and 0.01 mg/kg naloxone is provided along with a simple protocol for the mixing and administration of the drugs in emergencies.

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