Abstract

The genetic polymorphism at apo E locus has been determined among the Kshatriya (n=182) and the Mala (n=38) populations from Andhra Pradesh, India. No significant difference was found in genotype frequencies between the two populations. The sample of the two populations were pooled and called as the Indian sample. The gene frequencies for apo ε2, ε3 and ε4 alleles were 0.0500, 0.8636 and 0.0864, respectively. The allele frequencies of the Indian sample were compared with other Asian populations using χ2 test and cluster analysis. The Indian sample differs significantly with most of the Chinese populations and shows similarities with Japanese populations and the Indian sample clusters with Japanese populations.

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