Abstract
A fetal death in utero causes a prothrombotic environment due to abnormal placental anastomoses with hypoperfusion, which determines multisystem malformations, including dermal and subcutaneous involvement such as aplasia cutis and a central nervous system (CNS) abnormalities. We present the case of a quadruple pregnancy with death of a fetus at week 16, from which 3 live newborns were obtained, twin #1 with aplasia cutis type V. Twin #2 who did not present complications or associated malformations and twin # 3 with radiological documentation of dysgenesis of the corpus callosum. Based on literature, there is a relationship between chorionicity and the history of a papyraceous fetus and the multisystemic congenital malformations.
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