Abstract

Five researchers at the Johns Hopkins Applied Physics Laboratory (APL) received the APL invention of the year award for their device that can rapidly identify whether microbial pathogens are resistant to antibiotics. The prototype isoMS-drug-array depends on proprietary algorithms to interpret results of stable isotope mass spectrometry (MS) analyses. Once refined, this analytic package could be used for forensic purposes in homeland defense settings, in clinical microbiology laboratories, and for research and development of antimicrobial drugs, according to Plamen Demirev of APL and his fellow awardees Miquel Antoine, Andrew Feldman, Nathan Hagan, and Jeffrey Lin.

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