Apixaban reduced stroke and systemic embolism compared with aspirin in adults with AF for whom VKA therapy was unsuitable

Abstract

ACP Journal Club19 April 2011Apixaban reduced stroke and systemic embolism compared with aspirin in adults with AF for whom VKA therapy was unsuitableAndrew Dunn, MD, FACP, FHMAndrew Dunn, MD, FACP, FHMMount Sinai School of Medicine, New York, New York, USA (A.D.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-154-8-201104190-02003 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationConnolly SJ, Eikelboom J, Joyner C, et al. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011;364:806-17. https://pubmed.ncbi.nlm.nih.gov/21309657Clinical Impact RatingsGIM/FP/GP: Cardiology: Hematology: References1 Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361:1139-51. [PMID: 19717844] Google Scholar2 Connolly SJ, Pogue J, Hart RG, et al. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med. 2009;360:2066-78. [PMID: 19336502] Google Scholar3 Lopes RD, Alexander JH, Al-Khatib SM, et al. Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale. Am Heart J. 2010;159:331-9. [PMID: 20211292] Google Scholar4 Stroke Prevention in Atrial Fibrillation Investigators. Stroke prevention in atrial fibrillation study: final results. Circulation. 1991;84:527-39. [PMID: 1860198] Google Scholar Author, Article, and Disclosure InformationAffiliations: Mount Sinai School of Medicine, New York, New York, USA (A.D.)This article was published at Annals.org on 5 April 2011. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 19 April 2011Volume 154, Issue 8Page: JC4-3KeywordsAtrial fibrillationHemorrhageHospitalizationsIschemic strokeSafetyStrokeVitamin K ePublished: 19 April 2011 Issue Published: 19 April 2011 CopyrightCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...