Abstract
Apert syndrome or acrocephalosyndactyly is a rare genetic disease characterized by craniofacial dysmorphism and syndactyly of the hands and feet. We report an observation in a 4-month-old female infant, whose father was 65 years old. The infant was admitted to the neonatology of Sourô Sanou University Hospital (Burkina Faso) for respiratory distress in a congenital malformation disorders context with the notion of resuscitation for 10 minutes at birth. Her clinical examination revealed a craniofacial dysmorphism, syndactyly, choanal atresia, a cleft palate and a retardation of the psychomotor development. The paraclinical assessment consisted of a radiograph of the skeleton and a cerebral tomodensitometry confirming bicoronal synostosis and bone syndactyly; an abdominopelvic, cardiac ultrasound didn’t reveal any abnormalities; toxoplasmic serology was negative and rubella serology positive. The association of Apert syndrome with positive rubella serology seems fortuitous. Also, the association of choanal atresia and cleft palate has not commonly been reported in Apert syndrome. In the absence of surgical the infant has been followed until 9 months with therapeutic prospects.
Highlights
We report in this study, an observation of an Apert syndrome case of neonatal discov
N Apert syndrome or acrocephalosyno dactyly is a rare genetic disease characterized by craniofacial dysmorphism and syne dactyly of the hands and feet
According to Skidmore,[6] there is a possibility of antenatal diagnosis of Apert syndrome
Summary
Faso ery at Sourô Sanou University Hospital of Bobo-Dioulasso through which we illusly Abstract trate limits in diagnosis as well as in the management of this pathology in our context. N Apert syndrome or acrocephalosyno dactyly is a rare genetic disease characterized by craniofacial dysmorphism and syne dactyly of the hands and feet. Her e clinical examination revealed a craniofacial dysmorphism, syndactyly, choanal atresia, a m cleft palate and a retardation of the psychomotor development.
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