Aortic pulse wave morphology in individuals after chronic stroke: interarm comparison wave morphology after chronic stroke

Abstract

ContextVascular changes can be a risk factor for recurrent and new events of stroke. However, few information is known regarding the variables related to aortic pulse wave morphology in stroke individuals.ObjectiveTo analyze aortic pulse wave morphology (arterial stiffness indices, hemodynamics and vascular variables) and to compare the paretic and non-paretic sides in individuals after chronic stroke.DesignIn this cross-sectional study stroke individuals had arterial stiffness indices, hemodynamics and vascular variables assessed with brachial artery oscillometry. T-test (CI95%) was used in order to compare the variables between the paretic and non-paretic sides.ResultsTwenty individuals were included, 65% men (60.3 SD 16.7 years). The following variables: (mean difference [CI95%]): coefficient of reflection (−2.33 [−4.60 to −0.07]), peak of ejection wave, P1 (5.32 [2.75 to 7.90] and peak of ejection wave, P2 (6.17 [2.55 to 9.78]), central diastolic blood pressure (mean difference [IC95%]): (−3.75 [−6.09 to −1.40]), central systolic blood pressure (−6.17 [−9.74 to −2.59]), mean arterial pressure (−4.46 [−7.08 to −1.84]), peripheral diastolic blood pressure (−3.48 [−5.94 to −1.02]) and peripheral systolic blood pressure (−5.53 [−9.54 to −1.52]) were higher in paretic than non-paretic side. Hemodynamics parameters were similar in both sides.ConclusionsIn this study we demonstrated, for the first time, that many parameters from aortic pulse wave were higher in paretic compared with non-paretic side in individuals after chronic stroke, suggesting that peripheral vascular changes affect heart-vascular coupling in these individuals.