Abstract
Background Aortic blood flow in healthy people is characterised by helical flow in the ascending and descending aorta, with corresponding patterns of wall shear stress (WSS) imposed upon the wall of the aorta by moving blood. Flow and WSS patterns in the aortic root and sinuses of Valsalva, and the flow patterns in diseased aortas are incompletely defined. We describe the use of a validated, time-resolved, 3D flow MRI sequence to characterize flow and WSS in the aorta, focusing on the aortic root, and demonstrate the flow and WSS in the aorta of healthy volunteers and patients with prior aortic dissection.
Highlights
Aortic blood flow in healthy people is characterised by helical flow in the ascending and descending aorta, with corresponding patterns of wall shear stress (WSS) imposed upon the wall of the aorta by moving blood
We describe the use of a validated, time-resolved, 3D flow MRI sequence to characterize flow and WSS in the aorta, focusing on the aortic root, and demonstrate the flow and WSS in the aorta of healthy volunteers and patients with prior aortic dissection
All healthy subjects showed retrograde systolic flow jets in the sinuses of Valsalva, with corresponding negative systolic mean axial wall shear stress (-0.22N/m2 ± SD 0.05) at this level compared to positive values at all other aortic levels
Summary
Aortic dissection: visualisation of aortic blood flow and quantification of wall shear stress using time-resolved, 3D phase-contrast MRI. Alex Pitcher1*, Tom E Cassar, Paul Leeson, Jane M Francis, Edward Blair, Paul B Wordsworth, J Colin Forfar, Steffen E Petersen, Michael Markl, Stefan Neubauer. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011
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