Abstract

BackgroundPatients affected by acute central nervous system (ACNS) infectionsmay present different complications, including neuropsychological disorders. Nevertheless, psychopathological impairment has been rarely measured by appropriate and validated tests.Material and methodsSurvivors of childhood ACNS infections admitted to the Bambino Gesù Children’s Hospital, Rome, Italy, from June 2013 to June 2015 were re-evaluated at follow-up from June 2016 to June 2017. Both patients and their parents underwent a psychological interview and neuropsychological tests (the Leiter International Performance Scale – revised (Leiter-R), the Child Behaviour Checklist (CBCL), the K-SADS-PL test).ResultsThirty children were included in the study. The mean score of IQ and fluid reasoning was within the normal range. A percentage of 20% of the children enrolled showed criteria for generalized anxiety disorder.ConclusionOur study revealed the importance of follow-up evaluations after ACNS infections, in order to prevent mayor psychological sequelae and to perform treatment or rehabilitation.

Highlights

  • Patients affected by acute central nervous system (ACNS) infectionsmay present different complications, including neuropsychological disorders

  • During the period study, 84 children were admitted for ACNS infections to our hospital

  • Our study revealed that some patients admitted because of ACNS infections, in particular affected by meningitis, Table 2 Bivariate analysis on clinical and epidemiological variables

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Summary

Introduction

Patients affected by acute central nervous system (ACNS) infectionsmay present different complications, including neuropsychological disorders. Material and methods: Survivors of childhood ACNS infections admitted to the Bambino Gesù Children’s Hospital, Rome, Italy, from June 2013 to June 2015 were re-evaluated at follow-up from June 2016 to June 2017. Both patients and their parents underwent a psychological interview and neuropsychological tests (the Leiter International Performance Scale – revised (Leiter-R), the Child Behaviour Checklist (CBCL), the K-SADS-PL test). Somatic problems, like aches, headaches, nausea, Aim of the study The current study aims to investigate whether children previously affected by ACNS infection develop any neuropsychological impairment measured with validated tests, during a longer follow-up observation

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