Anxiety, depression, and cough and health related quality of life in bronchiectasis

Abstract

Background: Chronic respiratory diseases contribute to the development of anxiety and depression. In bronchiectasis (BE), it is unclear whether these comorbidities are related to general or disease-related quality of life (HRQoL) or symptoms. Aims: To evaluate the correlation between anxiety and depression and QoL in patients with BE. Methods: 26 subjects with non-cystic fibrosis BE of both sexes, 56±16 years, classified by the Bronchiectasis Severity Index (BSI), answered to the Mini Mental State Examination (MMSE), Anxiety and Depression Scale (HADS), Medical Outcomes Study 36 – Item Short – Form Health Survey (SF-36), Leicester Cough Questionnaire (LCQ) and Quality of Life in Bronchiectasis (QoLB). Results: According to the BSI, 15% of the participants presented high scores BE, 50% intermediate and 35% low, and all were considered to be able to answer the questionnaires, MMSE (25.84±2.70). Rates of anxiety and depression were 5.6±4.22 and 5.24±3.19, respectively. There were significant correlations (p Conclusions: The perception of anxiety was related to domains that refer emotional state in the SF-36. QoLB, however, correlated with all the domains of the LCQ, suggesting the relation between cough and anxiety. Depression was related to HRQoL only when evaluated by SF-36.