Abstract
The coronavirus disease 2019 (COVID-19) virus is a public health emergency of international concern, without known effective pharmaceutical treatment so far. It is difficult to treat infected patients who are experiencing acute respiratory failure, liver or cardiac injury, gastroenteritis and many other complications without any drug recommendation. Reducing the viral load is the most important key for Covid-19 treatment, where complication due to infection is highly correlated with the number of viral particles present in the lung and other organs of the patient. Most antivirals are effective against a wide range of viruses, where they inhibit viral development. Some of the possible antiviral treatment options for COVID-19 could be discovered from flu viral treatment that had led to quick respiratory illness recovery through reduction of viral load and viral shedding.
Highlights
Reducing the viral load is the most important key for Covid-19 treatment, where complication due to infection is highly correlated with the number of viral particles present in the lung and other organs of the patient
Some of the possible antiviral treatment options for COVID-19 could be discovered from flu viral treatment that had led to quick respiratory illness recovery through reduction of viral load and viral shedding
Significant decreased in viral load and viral shedding in participants infected with influenza; evidence from trial encompassing 3 influenza seasons from 2009-2011 in both the Northern and Southern Hemispheres involving 177 infected participants [2]
Summary
|| ISSN(online): 2589-8698 || ISSN(print): 2589-868X || International Journal of Medical and Biomedical Studies. Available Online at www.ijmbs.info NLM (National Library of Medicine ID: 101738825). ANTIVIRAL TREATMENT OPTIONS FOR COVID-19 BY REDUCTION OF VIRAL LOAD AND VIRAL SHEDDING Chandrika Murugaiah1* Liew Sat Lin Constance, Hassanain Al-Talib, Mehru Nisha 3, Tunung Robin, Tuan Zainazor Tuan Chilek, Atif Amin Baig, Rhanye Mac Guad, May Zaw Soe, Abm Tofazzal Hossain, Falah Abbas Mohamad Salih, Mustafa al Shagga7 1Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah 2Laboratory Medical Science Cluster, Faculty of Medicine, Universiti Teknologi MARA (UiTM) 3Clinical Laboratory Science Section, University Kuala Lumpur 4Universiti Putra Malaysia Bintulu Sarawak Campus 5Faculty of Fisheries and Food Science, University Malaysia Terengganu 6Faculty of Medical Sciences, University Sultan Zainal Abidin 7 University of Nottingham Malaysia.
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