Abstract
Diseases caused by viruses are a global threat, resulting in serious medical and social problems for humanity. They are the main contributors to many minor and major outbreaks, epidemics, and pandemics worldwide. Over the years, medicinal plants have been used as a complementary treatment in a range of diseases. In this sense, this review addresses promising antiviral plants from Marajó island, a part of the Amazon region, which is known to present a very wide biodiversity of medicinal plants. The present review has been limited to articles and abstracts available in Scopus, Web of Science, Science Direct, Scielo, PubMed, and Google Scholar, as well as the patent offices in Brazil (INPI), United States (USPTO), Europe (EPO) and World Intellectual Property Organization (WIPO). As a result, some plants from Marajó island were reported to have actions against HIV-1,2, HSV-1,2, SARS-CoV-2, HAV and HBV, Poliovirus, and influenza. Our major conclusion is that plants of the Marajó region show promising perspectives regarding pharmacological potential in combatting future viral diseases.
Highlights
Viruses are a global threat and, in addition to health problems, cause serious social problems to humanity
In Marajó, the leaves are used to prepare tea and baths that empirically help or bring some benefit for the treatment of flu and colds. To corroborate these antiviral reports, aromatic heterocycles of compounds isolated from the leaves and rhizomes of Alpinia zerumbet showed excellent antiviral activity for human immunodeficiency virus type 1 by the mechanism of inhibition Human Immunodeficiency Virus (HIV)-1 integrase and neuraminidase activity [11]
This study shows that the Marajó island (Amazon region), has a high diversity of
Summary
Gomes 1,2 , Luiza Martins 3 , Emilli Gomes 4 , Abraão Muribeca 2 , Sônia Pamplona 2 , Andrea Komesu 5 , Carissa Bichara 2 , Mahendra Rai 6 , Consuelo Silva 2,7 and Milton Silva 2, *. Faculty of Pharmaceutical Sciences, Federal University of Pará, Belem 66075-110, Brazil
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