Abstract

Antiretroviral activity of the new soft gelatin capsule formulation of saquinavir is better than that of the original hard gelatin capsule, although adverse effects and pill burden are higher. The poor bioavailability of the original formulation of saquinavir in hard gelatin capsules (HGC) led to an unfavorable antiretroviral response compared with that of other agents. In this study, saquinavir HGC …

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