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British Journal of Pharmacology and ChemotherapyVolume 31, Issue 2 p. 210-220 Free Access ANTIVIRAL ACTIVITY OF SODIUM FUSIDATE AND RELATED COMPOUNDS JENNIFER E. ACORNLEY, JENNIFER E. ACORNLEY Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorCHRISTINE J. BESSELL, CHRISTINE J. BESSELL Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorM. L. BYNOE, M. L. BYNOE Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorW. O. GODTFREDSEN, W. O. GODTFREDSEN Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorJ. MARY KNOYLE, J. MARY KNOYLE Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this author JENNIFER E. ACORNLEY, JENNIFER E. ACORNLEY Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorCHRISTINE J. BESSELL, CHRISTINE J. BESSELL Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorM. L. BYNOE, M. L. BYNOE Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorW. O. GODTFREDSEN, W. O. GODTFREDSEN Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this authorJ. MARY KNOYLE, J. MARY KNOYLE Medical Research Council Common Cold Research Unit, Salisbury; Glaxo Research Ltd., Stoke Poges, Buckinghamshire; and Leo Pharmaceutical Products, Ballerup, DenmarkSearch for more papers by this author First published: October 1967 https://doi.org/10.1111/j.1476-5381.1967.tb01992.xCitations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Anslow, W. K. & Fletcher, D. L. (1965). Personal communication. Barber, M. & Waterworth, P. M. (1962). Antibacterial activity in vitro of Fucidin. Lancet, 1, 931– 932. Buckland, F. E., Bynoe, M. L. & Tyrrell, D. A. J. (1965). Experiments on the spread of colds. II. Studies in volunteers with Coxsackie virus A21. J. Hyg., Camb., 63, 327– 343. Burton, H. S. & Abraham, E. P. (1951). Isolation of antibiotics from a species of Cephalosporium. Cephalosporins P1 P2, P3, P4 and P6. Biochem. J., 50, 168– 174. Cavallini, G., Massarani, E. & Nardi, D. (1964). Antiviral compounds IX. Steroid derivatives. J. med. Chem., 7, 673– 675. Chain, E., Florey, H. W., Jennings, M. A. & Williams, T. I. (1943). Helvolic acid, an antibiotic produced by Aspergillus fumigatus, mut. helvola. Yuill. Br. J. exp. Path., 24, 108– 119. Crosbie, R. B. (1963). Treatment of staphylococcal infections with “Fucidin.” Br. med. J., 1, 788– 794. Godtfredsen, W. O., Roholt, K. & Tybring, L. (1962). Fucidin, a new orally active antibiotic. Lancet 1, 928– 931. Godtfredsen, W. O., Von Daehne, W., Tybring, L. & Vangedal, S. (1966). Fusidic acid derivatives. Relationship between structure and antibacterial activity. J. med. Chem., 9, 15– 22. Halsall, T. G., Jones, Sir Ewart, R. H., Lowe, G. & Newall, C. E. (1966). Cephalosporin P1. Chem. Communs., pp. 685– 687. Harvey, C. L., Knight, S. G. & Sih, C. J. (1966). On the mode of action of fusidic acid. Biochemistry, Wash., 5, 3320– 3327. Johnsen, S. G. (1962). Fusidic acid and hormonally active steroids. Lancet, 2, 832. Tyrrell, D. A. J. (1963). The use of volunteers. Am. Rev. resp. Dis., 88, Suppl., pp. 128– 134. Wynn, V. (1965). Metabolic effects of the steroid antibiotic fusidic acid. Br. med. J., 1, 1400– 1404. Yamaki, H. (1965). Inhibition of protein synthesis by fusidic and helvolinic acids, steroidal antibiotics. J. Antibiot., Tokyo, ser. A., 18, 228– 232. Citing Literature Volume31, Issue2October 1967Pages 210-220 ReferencesRelatedInformation

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