Abstract

Urolithiasis is a complex process that occurs from series of several physiochemical event including supersaturation, nucleation, growth, aggregation and retention with the kidneys. Data from in vitro, in vivo and clinical trials reveals that phytotherapeutic agents could be useful as either alternative or an adjunct therapy in the management of urolithiasis. Casaurina equisetifolia have been reported to possess antiurolithiatic property by various folk lore practitioners. The in vitro antiurolithiatic study of the whole plant of C. equisetifolia through titrimetric and turbidity method was performed to check their potential in dissolving calcium oxalate crystals using Neeri as a standard compound. The aqueous extract and alcoholic extract of Gamma treated samples showed relatively higher dissolution of 70% of stones. Alcoholic extract of NPs and Gamma treated samples showed more dissolution than aqueous extract.

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