Abstract

A series of novel Hydroxylated 9,10-anthraquinone derivatives were designed and synthesized as potential antitumor agents starting from the natural product Emodin. The structures of the compounds were identified by NMR, ESI-MS and elemental analysis. Their antitumor activities against KLE cell line were tested by MTT assay. Some of them were found to exhibit a cytotoxicity profile more potent than Emodin on KLE cell line.

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