Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

Cornelia Tillack,Matthias Friedrich,Maria Koburger,Harald Vogelsang,Johannes Stallhofer,Andrea Bedynek,Ruediger Paul Laubender ,Laura Maximiliane Ehmann,Florian Beigel,Yvonne Dombrowski,Pavol Papay,Julia Diegelmann,Juergen Schauber ,J Glas ,Sarah Koglin,Johanna Wagner,Andreas Wollenberg,Martin Wetzke,Harald Maier,Stephan Brand

doi:10.1136/gutjnl-2012-302853

Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

Cornelia Tillack, Matthias Friedrich + Show 18 more

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https://doi.org/10.1136/gutjnl-2012-302853

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Journal: Gut	Publication Date: Mar 6, 2013
Citations: 270

Affiliation: Ludwig-Maximilians-Universität München, Medical University of Vienna, Institut für Medizinische Informatik, Biometrie und Epidemiologie, LMU Klinikum, Queen's University Belfast, Westfälische Hochschule, RWTH Aachen University, Hochschule Hannover, Hannover Medical School

#Psoriasiform Skin Lesions #Psoriasiform Lesions + Show 8 more

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Abstract

BackgroundWe analysed incidence, predictors, histological features and specific treatment options of anti-tumour necrosis factor α (TNF-α) antibody-induced psoriasiform skin lesions in patients with inflammatory bowel diseases (IBD).DesignPatients with IBD were...

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