Abstract

Transcatheter interventions enable safe and efficient treatment of various structural heart diseases. However, therapy does not finished with the end of the procedure. Device thrombosis is a possible serious complication. Therefore, careful patient management should include optimal antiplatelet or antithrombotic medication to enhance safe and complete endothelial coverage of the implanted device. In case of thrombus formation careful diagnostic evaluation and prompt treatment is crucial. This paper provides an update to current knowledge and understanding of prevention and management of device related thrombosis.

Highlights

  • MG both agree to be accountable for all aspects of the work

  • that questions related to the accuracy or integrity of any part

  • Treatment with oral anticoagulation for 3 months followed by ASA monotherapy lifelong was used after

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Summary

INTERATRIAL SHUNT DEVICES

Interatrial shunt devices were developed to reduce the left atrial pressure in patients with chronic heart failure with preserved EF (HFpEF) and with reduced EF (HFrEF) while avoiding excessive left to right shunting. Treatment with oral anticoagulation for 3 months followed by ASA monotherapy lifelong was used after V-Wave implantation [53, 58]. In patients after IASD implantation aspirin with clopidogrel for 6 months followed by ASA monotherapy lifelong were implemented and in those with indications for oral anticoagulation and/or antiplatelet therapy for a co-existing condition the preprocedural regimen was continued [55, 58]. This frail population should be assessed in terms of increased risk of bleeding during antithrombotic and antiplatelet treatment [58]

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