Abstract
Approaches to preventing recurrent stroke by antithrombocytic therapy are shown to be as diverse as its causes. The diagnosis of cardioembolic stroke in patients with atrial fibrillation should not limit the choice of an antithrombocytic agent to only oral (indirect) anticoagulants (OAC). If OAC cannot be used, antithrombocytic therapy, including combined (clopidogrel + ASA) one, may be considered as a reasonable alternative. Approaches to choosing the optimal antithrombocytic drug in noncardioembolic strokes are intricate since atherosclerosis is a systemic vascular disease and the poststroke period is characterized by a higher risk for not only recurrent stroke, but also for coronary catastrophes. It is concluded that an antithrombocytic agent should be chosen, by taking into account the multifocality of atherosclerosis, associated clinical conditions, diabetes mellitus, intravascular interventions and the individual risk of all cardiovascular events.
Highlights
Сосудистые заболевания головного мозга из-за высокой распространенности и тяжелых последствий для здоровья представляют важнейшую медицинскую и социальную проблему [1]
Approaches to preventing recurrent stroke by antithrombocytic therapy are shown to be as diverse as its causes
The diagnosis of cardioembolic stroke in patients with atrial fibrillation should not limit the choice of an antithrombocytic agent to only oral anticoagulants (OAC)
Summary
Сосудистые заболевания головного мозга из-за высокой распространенности и тяжелых последствий для здоровья представляют важнейшую медицинскую и социальную проблему [1]. Что терапия АСК менее существенно снижает риск повторного инсульта, уступая по эффективности варфарину. Предположение, что добавление клопидогрела к АСК позволит в большей степени уменьшить риск сердечно-сосудистых осложнений у больных с ФП, было положено в основу исследования ACTIVE A (Aspirin).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
