Abstract

This review covers publications during the period January 2015 to December 2015 on adverse reactions to antiseptic drugs and disinfectants. Specific agents discussed are aldehydes (formaldehyde and glutaraldehyde), guanidines (chlorhexidine, polyhexamethylene guanidine and polyhexamethylene biguanidine), benzalkonium compounds, cetrimide, ethylene oxide, halogens (sodium hypochlorite and povidone–iodine). No new data were identified for triclosan, tosylchloramide and phenolic compounds. Antiseptic drugs and disinfectants continue to be used in a variety of medical and occupational settings, in certain cosmetic products as well as in the household. An interesting observation has been published on cetrimide, a quaternary ammonium disinfectant. Because cetrimide is commonly used in combination with chlorhexidine, it was warned about the possibility of mislabeling of chlorhexidine allergy.

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