Abstract
Although it may be possible to target externally synthesized antisense RNA molecules to the right cell by using antibody-coated liposomes [6], the inhibitory effect achieved in this experiment was only transient, probably because of the short half-life of these molecules. It would therefore seem better to produce the antisense RNA inside the virus-infected cell in order to achieve a constant inhibitory concentration. To achieve this, experiments in vitro use vectors, often of retroviral origin, to stably transduce and express the antisense sequence of interest
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