Abstract
Our approach to the treatment of patients infected with the human immunodeficiency virus (HIV) has changed significantly over the past 2 years. This follows a number of recent advances which include a better understanding of HIV pathogenesis, the development of new techniques for sensitive and accurate quantification of HIV-1 RNA in plasma, availability of newer antiretroviral agents and the demonstration that combination therapy is more effective than monotherapy [1–6]. Consequently, there are now fewer HIV related deaths and opportunistic infections in addition to a reduction in hospital admissions and lengths of stay [7–8]. We review these recent advances and how they influence the management of HIV disease in the clinical setting.
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