Antiradical activity of 3-hydroxypyridine derivatives

Abstract

1. The authors have determined the antiradical activity of 3-hydroxypyridine derivatives, and have established the pattern of its variation with their chemical structure. 2. Incorporation of alkyl, hydroxy, methoxy, phenyl, and benzyl groups and condensed benzene rings into the β-pyridol ring, similarly to phenol, increases the antiradical efficiency of 3-hydroxypyridine. 3. The sharpest increase in antiradical activity is observed when hydroxy or methoxy groups are introduced into the hydroxypyridine ring of 2-phenyl-, 2- and 5-henzyl-3-hydroxypyridines.