Anti-quorum Sensing Systems and Biofilm Formation

Abstract

Bacterial communication process can be broadly classified into two categories such as chemical communication process (quorum sensing mechanism) and electrical communication system (controlled by potassium ion channels). Quorum sensing is a well-known density-dependent optimal survival strategy, which is mediated by chemical signalling molecules (autoinducers). Collective bacterial behaviour regulates the bacterial lifestyle on surface (i.e. biofilms). Bacterial cell-to-cell communication process and biofilms formation cause several infectious diseases. In this chapter, we mainly focus on anti-quorum sensing mechanism and biofilm formation (including nanofabrication) that form the point of view of experimental approaches as well as mathematical models. In the end, we point out some significant and fundamental experimental observations on anti-quorum sensing and biofilm formation.