Abstract
This chapter focuses on antipsychotic drugs. Hypotension is the most commonly observed cardiovascular adverse effect of antipsychotic drugs and it may be particularly hazardous in elderly patients. Many antidysrhythmic drugs prolong ventricular repolarization and cause torsade de pointes. An increasing number of non-cardiac drugs are reported to have similar effects; among them, antipsychotic drugs are particularly associated with conduction disturbances, torsade de pointes being one of the most worrisome. The chapter discusses the risk factors and drug interactions associated with antipsychotic drugs. In children and adolescents , antipsychotic drugs are used in general practice to treat psychotic disorders and a variety of nonpsychotic conditions, including autism, Tourette's syndrome, and mental retardation associated with behavioral problems or psychotic disorders. Untoward effects of antipsychotic drugs in children are similar to those found in adults.
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