Anti-prolactin Agent with Gonadotropin-releasing Hormone Synergistically Improve Egg Production in Indigenous Chicken via Regulating Broody Behavior

Abstract

Despite the indigenous chicken's many natural advantages, broodiness continues to be a substantial barrier to minimizing egg production and economic losses. Prolactin is the primary regulator of broodiness. As a result, the goal of our research was to see if lower prolactin levels can limit broodiness, resulting in increased egg production and increased economic value. Sixty indigenous chickens aged 18-20 weeks were divided into three groups of 20 hens each. One was left untreated, two were given GnRH (0.50 ml/bird @ S/C) with Anti-prolactin (Bromocriptine 640 g/bird/day @ orally), and three were given GnRH, Anti-prolactin, and cold therapy (1 time/day) for three months. The chickens were first given GnRH injections once a week for three weeks. It was given on the 13th day of egg production and continued for 10 days. After utilizing GnRH plus anti-prolactin medications for 13 days, the cold application was given every day at the same time. Hormone analysis, egg production, broody time, pause time was noted. Prolactin levels fell in all treatment groups. The number of egg production per clutch was significantly (p<0.05) increased in both treated groups, and the highest was recorded in GnRH plus anti-prolactin group (33eggs / clutch). Surprisingly, pause day and broody time significantly (p<0.05) decreased in the same Group B (7d, 4d respectively). Postmortem ovary analysis substantially supports the treatment group's finding against the control group. Overall, combining an anti-prolactin drug with GnRH enhances egg production by synergistically modulating broody behavior.