Abstract

The study of the chemical constituents of the whole plant of Elaeagnus umbellata has resulted in the isolation and characterization of three coumarins, namely, 7-Hydroxy-chromen-2-one (1), 7, 8-Dihyroxy-chromen-2-one (2), 3-(2,2,3,4,5-Pentahydroxy-hexyloxy)-chromen-2-one (3) and an anthraquinone (4) together with β-sitosterol glucopyranoside (5) and lupeol (6). The structural elucidation of the isolated compounds was established based on spectroscopic studies. The in vitro antimalarial activity of compounds 1 to 4 againstPlasmodium falciparum shows partial suppression of parasitic growth. Key words: Elaeagnus umbellata, coumarins, anti-malarial activity.

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