Abstract
AbstractAnti-phospholipid syndrome is a clinical and biological condition characterized by polymorphic clinical manifestations associated with the persistence of antiphospholipid antibodies. This disease mainly involves young women, although men or older people can also be affected. Most of clinical features are thrombotic (macro- and micro-vascular) and obstetrical manifestations. Some other signs are also described: cardiac, renal, cerebral or cutaneous. The detection of antiphospholipid antibodies antibody relies on titration methods (anti-cardiolipin and anti-β2GPl) but also hemostasis tests for which knowledge and experience of the techniques are needed to ensure the reliability of the results and enable the final APS diagnosis. The treatment of APS leans on anti-thrombotic therapies but also on treatments with corticosteroids or even immunosuppressives for more severe forms.
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