Abstract
In Reply .—The data of Taillan et al are interesting and confirm the presence of anticardiolipin antibodies in patients with human immunodeficiency virus infection. 1 We were struck by the frequency of anticardiolipin antibodies (29/74) in patients with asymptomatic human immunodeficiency virus infection, lending further support to the idea that the presence of elevated titers of anticardiolipin antibodies may be a reflection of the underlying viral infection. Although we are not entirely clear from the data provided how the actual frequency of the circulating lupus anticoagulant was obtained, they noted a high frequency (53.5%) using the tissue thromboplastin inhibition test. We prefer to use the kaolin clotting time method as described by Exner and coworkers 2 because it is not influenced by warfarin therapy and can be interpreted in the face of a prolonged prothrombin time.
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