Anti-phase microwave illumination-based thermoacoustic tomography for in vivo detection of rheumatoid arthritis in the finger joints

Zihui Chi,Xueliang Xu,Dan Wu,Lin Huang,Huabei Jiang,Xiaojun Long

doi:10.1109/imbioc52515.2022.9790169

Anti-phase microwave illumination-based thermoacoustic tomography for in vivo detection of rheumatoid arthritis in the finger joints

Zihui Chi, Xueliang Xu + Show 4 more

https://doi.org/10.1109/imbioc52515.2022.9790169

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Publication Date: May 16, 2022

Affiliation: Chongqing University of Posts and Telecommunications, Chengdu University of Traditional Chinese Medicine, University of Electronic Science and Technology of China, University of South Florida

#Thermoacoustic Tomography #Finger Joints + Show 8 more

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Abstract

Rheumatoid arthritis (RA) impacts about 1% of the population worldwide. Here, anti-phase microwave illumination-based thermoacoustic tomography (TAT) was used to in vivo detect RA in the finger joints. Magnetic resonance imaging (MRI) was performed to verify TAT findings. The results showed that the anti-phase TAT images of the RA joints displayed abnormalities compared to the healthy ones, and they matched well with the MRI images. These prove that anti-phase TAT is able to visualize bone marrow edema and synovitis, which are important features associated with early RA. This work provides a foundation for further TAT development and validation of clinical application in detection of RA.

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