Antiparasitic and physiological evaluation of Curcuma longa extract and/or PZQ on Schistosoma mansoni infected mice.

Marwam Aboueldahab,Enasa Elhussieny

doi:10.21474/ijar01/654

Abstract

Antiparasitic and physiological evaluation of Curcuma longa extract and/or PZQ on Schistosoma mansoni infected mice.

Highlights

One of the causative agents of the disease is a trematode worm, Schistosoma mansoni (Bos et al, 2009)
In 2012 was reported that Egypt is the MENA (Middle East North African) country with the highest prevalence (7.2 out of 80.4 million people, about 9%) of schistosomiasis, in spite of the many efforts to control this parasitic infection over many years ago (El-Khoby et al, 2000)
The drug of choice for treating all schistosome species is Praziquantel (PZQ).It was developed in the late 1970s (Seubert et al, 1977) and has become the only available drug used in control programs (Doenhoff et al, 2008).this drug is not effective in the treatment of immature forms or preventing re-infection (Magnussen, 2003)

Summary

Introduction

One of the causative agents of the disease is a trematode worm, Schistosoma mansoni (Bos et al, 2009). S. mansoni infected and treated groups with multiple doses of Curcumin extract accompanied with PZQ or PZQ only resulted in a highly significant (P

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Results

Conclusion