Abstract
Oxidative stress represents a condition in which there is an imbalance between the production of free radicals and their removal. Many risk factors, including alcohol, drugs, environmental pollutants, radiation, infective agents can induce oxidative stress in the liver leading to the functional disturbance of the liver cells. In order to reduce oxidative stress, modern medicine goes back to the natural substances, which are becoming increasingly popular both in prevention and in treatment of many diseases. Numerous hepatoprotective substances such as silymarin, spirulina, pumpkin oil and whey are used in traditional diets by many people. Some experimental studies on animals and the monitoring of the effects on humans showed that whey can be estimated as an important antioxidant in the treatment of liver diseases. New information obtained on the basis of controlled experimental and clinical studies of its effects in terms of protection or treatment of already existing changes in the liver tissue, certainly contribute to defining the concrete possibilities of potential use in therapeutic methods, either as a supplement or extrication of specific medicinal ingredients.
Highlights
Nova saznanja dobijena na osnovu kontrolisanih eksperimentalnih i kliničkih studija o njenim efektima u smislu protekcije ili saniranja već nastalih promena na jetrinom tkivu, doprinose svakako i konkretnijem definisanju mogućnosti potencijalne primene u terapeutskim postupcima, bilo kao suplementa ili izdvajanjem konkretnih lekovitih sastojaka
Kod pacijenata sa nealkoholnim steatohepatitisom koji su uzimali izolat surutke došlo je do povećanja aktivnosti glutationa, smanjenja nivoa ALT i AST i jasnog povlačenja steatoze na CT-u, pa se u ovoj studiji navodi da proteini surutke bogati cisteinom imaju značaj kao suplement u terapiji ove bolesti [22]
New information obtained on the basis of controlled experimental and clinical studies of its effects in terms of protection or treatment of already existing changes in the liver tissue, certainly contribute to defining the concrete possibilities of potential use in therapeutic methods, either as a supplement or extrication of specific medicinal ingredients
Summary
Oksidativni stres predstavlja stanje u kome postoji neravnoteža između stvaranja slobodnih radikala i njihovog uklanjanja. Uključujući alkohol, lekove, zagađivače životne sredine, radijaciju, infektivne agense, mogu indukovati oksidativni stres u jetri koji dovodi do poremećaja funkcije jetrinih ćelija. Brojne hepatoprotektivne supstance kao što su silimarin, spirulina, tikvino ulje i surutka se koriste u tradicionalnoj ishrani mnogih naroda. U nekim eksperimentalnim studijama na životinjama kao i praćenjem efekata kod primene na ljudima, surutka se pokazala kao značajan antioksidans u lečenju bolesti jetre. Nova saznanja dobijena na osnovu kontrolisanih eksperimentalnih i kliničkih studija o njenim efektima u smislu protekcije ili saniranja već nastalih promena na jetrinom tkivu, doprinose svakako i konkretnijem definisanju mogućnosti potencijalne primene u terapeutskim postupcima, bilo kao suplementa ili izdvajanjem konkretnih lekovitih sastojaka
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
