Abstract
Guanylic, polyadenylic, and adenylic acids were tested for their abilities to inhibit hydrogen peroxide oxidation of the base moieties of polycytidylic and polyuridylic acids. Guanylic acid protected both of these substrates, but adenylic acid protected neither. Polyadenylic acid showed antioxidative capacity only when complex formation could occur, i.e., in the presence of polyuridylio acid. The chelating agent, ethylenediaminetetraacetic acid, was as effective as guanylic acid in protecting both pyrimidine substrates.
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