Abstract
The aim of this study is to present a documentation about the antioxidants used in pet feed, and the toxicity exerted on pets. Natural and artificial antioxidants are used in the industry of pet feed to protect oils and fats against lipid peroxidation or oxidative rancidity. In the present paper 4 brands of moist and dry feed were analysed. In order to determine the toxicity of the antioxidants used in pet feed, some literature studies regarding genotoxicity, teratogenicity, carcinogenity, allergen potential and fetotoxicity were consulted. After revising the literature we found that: ADI for BHA was established 100 mg/kg bw/day. The NOAEL for a 90 days study was 62,5 mg/kg bw; In a long therm study the NOAEL was 250 mg/kg bw; at reproductive and developmental levels the NOAEL was 0.125 mg/ kg bw and at teratogenic level the NOAEL was 400 mg/kg bw. LD was 2000 mg/kg bw. Following the studies results we can conclude that: TBHQ (BHA secondary metabolite) has 50 carcinogenic effect; TBHQ has genotoxic effect; BHA has no teratogenic effect; BHA has allergen potential.
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