Abstract
The aim of this study was to investigate whether there was any difference in the levels of antioxidant agents in the immune system between essential hypertension in pregnancy and pregnancy-induced hypertension (PIH). The functions of T and B lymphocytes were analysed by lymphocyte response to mitogens and the ability to secrete immunoglobulins, respectively. Interleukin-2 (IL-2) production from lymphocytes was also determined by bioassay. Five antioxidant agents–superoxide dismutase (SOD), plasma thiol (PSH), red cell lysate thiol (LSH), plasma glutathione (GSHp) and red cell membrane thiol (MSH)–were measured enzymatically and spectrophotometrically. The results showed that there was no significant difference in mitogenic activity between normal pregnancy and essential hypertension. However, phytohaemagglutinin-induced mitogenic activity was increased in patients with PIH compared to patients with essential hypertension and normal pregnancy. IL-2 production in patients with PIH was also significantly hig...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.