Antioxidant potential and DPPH radical scavenging kinetics of water-insoluble flavonoid naringenin in aqueous solution of micelles

Abstract

Abstract The antioxidant performance of flavonoid naringenin was investigated in terms of the DPPH free radical scavenging activity (RSA) in different aqueous micellar media using UV–vis spectrophotometric technique. The DPPH assay was done at (25.0 ± 0.1) °C and various concentrations of anionic amphiphile of sodium dodecylsulfate (SDS) and cationic amphiphile of cethyltrimethylammonium bromide (CTAB). The kinetics of the antioxidant behavior of naringenin was also evaluated in the micelle systems. The RSA values and kinetic data obtained in the model self-assembled system demonstrate that activity and rate of the DPPH radical scavenging increase with increasing concentration of micelles SDS and CTAB. It was found that these abilities in SDS solution are higher compared to that in the colloidal aggregated CTAB surfactant. Finally, the micellar effects on the antioxidant efficiency were explained in terms of possible interaction modes between naringenin and the micellar surfaces.