Abstract
We studied the systemic effect of photodynamic therapy (PDT) in experimental animals at PDT local exposure on their radiation-induced ulcer (the local skin irradiation dose of 85.0 Gr) infected with S. aureus. Lipid peroxidation (LPO) products (malondialdehyde, diene conjugates) were determined in blood serum. LPO levels were measured by conventional techniques. It was found that the values of pro oxidant markers concentration (2.0-2.5 fold increased diene conjugates level, 30-40 % increased malondialdehyde content in the infected group), which dramatically increased after local irradiation of the outer surface of thigh and, especially, after infection of the wound surface, at PDT treatment restored to normal levels. Keywords: infected radiation ulcer, photodynamic therapy (PDT), lipid peroxidation (LPO), malondialdehyde (MDA), diene conjugates (DC).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
