Abstract
Abstract − Strawberry is widely consumed in diet and has been attracted much attention due to its potential forhuman health benefits. Strawberry contains a diverse range of phytochemicals but the biological activities withmolecular mechanisms are poorly elucidated yet. In this study, the effects of the extracts of strawberry (Maehy-ang cultivar) on antioxidant, antiinflammatory, and antiproliferative potential against various cancer cells wereinvestigated. The strawberry extracts (SE) of Maehyang cultivar showed 1,1-diphenyl-2-picrylhydrazyl (DPPH)free radical scavenging activities. In addition, SE inhibited the growth of human colon (HCT-116), lung (A549),stomach (SNU-638) and fibrosarcoma (HT-1080) cancer cells. The strawberry extracts also exhibited the inhib-itory effect on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production and suppressed LPS-inducedinducible nitric oxide synthase (iNOS) protein and mRNA expression in mouse macrophage RAW 264.7 cells.These findings suggest that the strawberry extracts (Maehyang cultivar) might have antioxidant, antiinflam-motry, and anticancer activities.
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