Abstract
Context: Preeclampsia is a multisystem disorder, although the cause is unknown, yet oxidative stress is a prominent feature; therefore, assessment of oxidative stress indices in preeclamptics would no doubt improve their clinical outcome. Aim: The aim of this study was to determine the antioxidant and malondialdehyde (MDA) status in preeclampsia. Setting and Design: This was a cross-sectional descriptive study. Subjects and Methods: One hundred and ninety-six (196) respondents consisting of 124 preeclampsia (PE), 36 normotensive pregnant women (NPW), and 36 analbuminuric hypertensive pregnant women (AHPW) participated in this study. Blood samples were collected for estimation of plasma uric acid, serum MDA, nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase (GSSH) and catalase (CAT) activities, Vitamin C (Vit C), and Vitamin E (Vit E) using standard methods. Statistical Analysis Used: The Statistical Package for the Social Sciences version 16 with level of significance set at P
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