Abstract
The antioxidant and hepatoprotective activity of Tetrapleura tetraptera extracts in carbon tetrachloride (CCl 4)-induced liver injury in rats was investigated. T. tetraptera extracts showed varying levels of protective action against CCl 4-induced liver damage as evidenced through the significant reduction in the activities of serum marker enzymes for liver damage (alanine transaminase, aspartate transaminase, and alkaline phosphatase), and bilirubin levels when compared with CCl4intoxicated control rats. The extracts decreased the elevation in the activities of the enzymes in the liver. They also protected against CCl 4 induced lipid peroxidation. The extracts reduced CCl4-liver induced necrosis in dose dependent manner. These results indicated that fruit extracts of T. tetraptera possess a hepatoprotective property against CCl4induced liver damage which was mediated through its antioxidative defenses.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
