Antioxidant and Antityrosinase Activities of Various Extracts from the Fruiting Bodies of Lentinus lepideus

Ki Nam Yoon,Young Bok Yoo,Nuhu Alam,Tae Soo Lee,Kyung Rim Lee,Jong Chun Cheong,Pyung Gyun Shin

doi:10.3390/molecules16032334

Ki Nam Yoon, Young Bok Yoo + Show 5 more

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https://doi.org/10.3390/molecules16032334

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Abstract

Lentinus lepideus is an edible mushroom currently available in Korea. The acetone, methanol and hot water extracts were prepared and assayed for their antioxidant and antityrosinase inhibitory activities. The hot water extract showed the strongest β-carotene-linoleic acid inhibition compared to the other extracts. At 8 mg/mL, the methanolic extract showed a high reducing power of 1.21. The acetone and methanol extracts were more effective in scavenging DPPH radicals than the hot water extract. The strongest chelating effect was obtained from the methanolic extract. Xanthine oxidase and tyrosinase inhibitory activities of the acetonic, methanol and hot water extracts increased with increasing concentration. Gallic acid, chlorogenic acid, vanillin, naringin, naringenin, formononetin, and biochanin-A were detected in the acetonitrile and hydrochloric acid (5:1) solvent extract. This study suggests that fruiting bodies of L. lepideus can potentially be used as a readily accessible source of natural antioxidants.

Highlights

IntroductionTricholomaceteae, order Agaricales [1]
Lentinus lepideus, commonly known as the train wrecker mushroom, belongs to the familyTricholomaceteae, order Agaricales [1]
Mushrooms contain various polyphenolic and flavonoid compounds recognized as good antioxidants [3]

Summary

Introduction

Tricholomaceteae, order Agaricales [1] It grows on the wood of pine and other conifers, and seems to prefer railroad ties, bridge timber, old logs and stumps. It is one of the popular edible mushrooms in. Mushrooms have been used in Asia as foods and medicines. Mushrooms contain various polyphenolic and flavonoid compounds recognized as good antioxidants [3]. Several important compounds including polysaccharides (β-glucan), ergosterol, vitamins, α-tocopherol and β-carotene have been isolated from the mushrooms. Recent studies have shown that medicinal properties of mushrooms include anti-tumor, antimicrobial, liver function improving, and blood pressure and cholesterol lowering activities [4]

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