Antioxidant and Antiradical Properties of Resveratrol and Its Antistress Activity

Abstract

The antiradical properties and biological activity of natural polyphenol—resveratrol—are studied. The chemiluminescence method recorded high values of the antiradical activity of this drug. Using the model system, it is shown that the drug in the concentration range of 10–5 to 10–12 M prevented the activation of lipid peroxidation (LPO) in the mitochondrial membranes of pea seedlings, which could indicate the presence of antistress properties in this preparation, which are studied under conditions of water deficiency, which causes LPO and leads to mitochondrial swelling. Resveratrol seed treatment (3 × 10–5 M) under these conditions leads to a decrease in the number of swollen mitochondria and the appearance of small mitochondria, which, perhaps, is a sign of the activation of mitochondrial biogenesis. Resveratrol, which prevents LPO, helps maintain the functional state of mitochondria and activates the energy metabolism by increasing their number, which is reflected in the physiological parameters: the drug prevents a decrease in the growth rate of pea seedlings in conditions of water deficiency. Based on the data obtained, it is assumed that the drug has antistress properties in the concentration range in which it exhibits an antioxidant effect.