Abstract
In this study, antioxidant activity of the hot water extract of Pluchea indica tea leaves (HWEP) was measured by assays for radical scavenging against 1,1-diphenyl-2-picrylhydrazyl, superoxide and hydroxyl radical, ferric ion reducing power, as well as ferrous ion chelating. Results showed that HWEP exhibited good antioxidant activity in all test systems in a concentration-dependent manner. Furthermore, HWEP has potent inhibitory effects against lipopolysaccharide-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production in RAW 264.7 macrophages. The hot water extract of P. indica leaves contains a source of antioxidants and inhibitors of NO and PGE2 production that can be used as dietary supplements containing good health promoting effect. Key words: Anti-inflammatory activity, antioxidant activity, herbal tea, Pluchea indica.
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