Abstract
Objective: In the present study, the essential oil, methanol extract, and methanol fractions (n-hexane, chloroform, ethyl acetate, and n-butanol) obtained from Commelina nudiflora were investigated for the free radical scavenging effects and phytochemical analysis.Methods: The antioxidative effect of the essential oil, methanol extracts and methanol fractions were evaluated using 2, 2 diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Total phenolic and flavonoid contents were determined using Folin-Ciocalteau and aluminium chloride reagents respectively. The phytochemical analyses of the essential oil, methanol extracts and methanol fractions were performed by gas chromatography and mass spectrometry (GCMS). Results: The antioxidant, total phenolic and total flavonoid contents of butanol, ethyl acetate and chloroform fractions were higher followed by methanol extract, hexane fraction and essential oil. Phytochemical analysis indicated the presence of alkaloid, saponin, steroid, phytosterols, triterpenoids and tannins etc. The identified bioactive constituents of essential oil, methanol extract and methanol fractions of C. nudiflora were indole, 2-methoxy-4-vinylphenol, 2-pentadecanone, 6,10,14-trimethyl, phenol, benzyl alcohol, eugenol, phenol, 2, 4-bis (1,1-dimethylethyl), hexadecanoic acid, ethyl ester (palmitic acid ester), n-hexadecanoic acid (palmitic acid), 9, 12-octadecadienoic acid, (linoleic acid) and phytol. All identified bioactive compounds and their derivatives were generally reported with antimicrobial, antioxidant, anti-inflammatory and antitumor properties.Conclusion: The obtained data suggest that the essential oil, methanol extract and methanol fractions of C. nudiflora possess remarkable antioxidant activities and vital phytochemicals. Thus the plant can be a utilized as a potential source of nutraceutical with antioxidant activity.
Highlights
Prepared drugs are utilized worldwide for the treatment of various diseases
In the current study, the essential oil, methanol extract, and methanol fractions obtained from Commelina nudiflora were investigated for the free radical scavenging effects and phytochemical analysis
The data recorded in the current study showed that the phenolic compound level in butanol, ethyl acetate, chloroform fractions and methanol extract of C. nudiflora is very high
Summary
Prepared drugs are utilized worldwide for the treatment of various diseases These drugs have several side effects such as gastric ulcer, kidney damage as well as cardiac abnormities [1]. In India, the young stem of the plant is steamed and eaten as a vegetable in daily diet [6] while the young leaves and small flowers are consumed fresh in salads or boiled with butter [7, 8]. As the plant is used for the treatment of various diseases but no research has been done to explain the phytochemical compassion and free radical scavenging effects of the essential oil and solvent extract. In the current study, the essential oil, methanol extract, and methanol fractions obtained from Commelina nudiflora were investigated for the free radical scavenging effects and phytochemical analysis
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
