Abstract

The antioxidant activity of pomegranate fruit peels was evaluated using in vitro tests. 80% methanolic extracts (ME) of peels had higher yield (45.4%) and total phenolics (27.4%) than water (WE) or ether extracts (EE). The reducing power of ME was more potent (P α-catechin. Pomegranate peels contained phenolics, exhibited DPPH scavenging activity and reducing power.

Highlights

  • There is increasing epidemiological and pharmacological evidence that plants contain biologically active components offering health benefits and protection against degenerative diseases

  • Uncontrolled generation of free radicals is associated with lipid and protein peroxidation, resulting in cell structural damage, tissue injury or gene mutation [3,4]

  • Pomegranate peels were extracted with solvents of a different polarity

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Summary

Introduction

There is increasing epidemiological and pharmacological evidence that plants contain biologically active components (e.g. free radical scavengers) offering health benefits and protection against degenerative diseases. Oxygen radicals and lipid peroxides have been known for their alleged role in the etiology of many in vivo pathological reactions such as aging and cancer. In this regard, epidemiological studies have shown that consumption of fruits and vegetables is inversely associated with morbidity and mortality of cardio- and cerebro-vascular diseases and certain types of cancers [1,2]. Uncontrolled generation of free radicals is associated with lipid and protein peroxidation, resulting in cell structural damage, tissue injury or gene mutation [3,4]. It was stated that besides their endogenous defenses, the consumption of dietary antioxidants, such as phenolic compounds, play a vital role in protecting against ROS

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