Antioxidant activity of extracts of oregano and marsh cinquefoil, growing in the Altai region, in connection with their content of favonoids

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Drugs based on medicinal plants have such advantages over synthetic analogues as low toxicity, better tolerability and reduced risk of addiction. Antioxidant agents in medicinal plants include substances from the flavonoid group, due to their ability to inactivate free radical processes, due to the mechanism of electron transfer between reaction components to neutralize free radicals. Among the medicinal plants of Western Siberia and the Altai Territory, oregano and marsh cinquefoil have a high content of flavonoids. The purpose of the study was to evaluate the antioxidant activity of alcohol-free extracts of oregano and marsh cinquefoil growing in the Altai region in connection with the content of flavonoids (flavonols and proanthocyanidins). To conduct the study, alcohol-free extracts of the studied plants were prepared using patented technology. The content of flavonols and proanthocyanidins was studied by arbitration techniques using spectrophotometry. The antioxidant activity of the extracts was measured using cathodic voltammetry method. The results showed that the average flavonol content in oregano extract was 866.5 μg/ml, while only traces were found in the extract of cinquefoil (60.0 μg/ ml). The average content of proanthocyanidins in the extract of cinquefoil was 4.05%, in the extract of oregano content of proanthocyanidins was 0.43%. The average coefficient of antioxidant activity for cinquefoil extract was 11.63 mmol/l×min and 3.81 mmol/l×min for oregano extract. From the results obtained, we can conclude that it is advisable to use extracts of marsh cinquefoil and oregano, growing in the Altai Territory, in the composition of biologically active antioxidant additives.