Abstract
The antioxidant properties oí Acantholippia deserticola, a herb used in traditional northern Chilean medicine was studied using free radical-generating systems. The 50% aqueous-ethanol extract oí Acantholippia deserticola protected against non-enzymatic lipid peroxidation in microsomal membranes of rat, induced by an Fe++-ascorbate system and measured spectrophotometrically by the TBARS test, and had strong free radical scavenging capacities on stable ABTS and DPPH radicals. The results shows that the IC50 value of the 50% aqueous-ethanolic extract of A.deserticola is 18 +/- 0.5 microg/mL in DPPH radical-scavenging, 15 +/- 0.8 microg/mL in lipid peroxidation , Total Antioxidant Activity (TAA) is 0.95 mM of Trolox per mg/mL of extract. The total phenolics content of extract is 725 +/- 12 mg of gallic acid equivalent per g of dried extract. The results indicate that the 50% aqueous-ethanol extract of Acantholippia deserticola clearly has antioxidant properties.
Highlights
The “Puna atacameña” is located approximately 250-300 km to the northeast of city of Antofagasta in northern Chile, near the borders with Bolivia and Argentina
Antioxidant activity of Acantholippia deserticola 50% ethanol - extract has been found by means of free radical scavenging assays (DPPH and ABTS tests) and lipid peroxidation
The results of this study clearly show that Acantholippia deserticola has excellent antioxidant activity
Summary
The “Puna atacameña” is located approximately 250-300 km to the northeast of city of Antofagasta in northern Chile, near the borders with Bolivia and Argentina. The area is a particular biotope, characterized by varying altitudes of between approximately 3,000 and 4,200 meters above sea level [1]. The inhabitants of the “Puna atacameña” must support climatic inclemency, and remarkable isolation due the great distances that separate them from urban centers - more than 200 Km of distance. This explains the great knowledge about and the intense use of medicinal herbs, which are still an important and essential part of everyday life [3,4,5,6]
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