Abstract
Background: Antioxidants play a significant role to protect harm caused by oxidative stress (OS). Plants having phenolic substances are reported to possess antioxidant properties. The present study was intended to research the antioxidant potential of aqueous extract, Hydroalcoholic extract and Alcoholic extract from Martynia annua root. Martynia annua (cat’s claw, bichu) belongs to Martyniaceae family. For centuries, extracts of leaves, roots, stems, roots and seeds of M. annua have been used to cure eplilepsy, inflammation, tuberculosis, skin infections etc. Methods: The antioxidant activities of Aqueous, Hydroalcoholic and Alcoholic extractives were evaluated by using DPPH free radical assay. DPPH (1,1-diphenyl-2-picrylhydrazyine) free radical analysis is one of the accurate and frequently employed method for evaluating antioxidant activity. Results: Aqueous, Hydroalcoholic and Alcoholic extracts of Martynia annua root were explored which revealed that with increase in concentration of extracts resulted in increased degree of reduction. The IC50 values were calculated for all three extracts. Ascorbic acid was used as control. Martynia annua exhibited IC50 of 69.58±3.44µg/ml, 70.91±2.91µg/ml & 68.49±3.15µg/ml for Hydro-alcoholic extract, aqueous extract & ethanolic extract respectively while Ascorbic acid exhibited IC 50 of 62.91±2.85µg/ml. Conclusions: Scientific evidence suggests that antioxidants reduce the risk for chronic diseases including cancer and heart disease and infectious diseases. Further evaluation of pharmacological activities and cell line studies of Martynia annua may prove useful in treatment of cancer and heart diseases.
Highlights
Antioxidants play a significant role to protect harm caused by oxidative stress (OS)
*Corresponding Author: Rahul Kumar Gupta, PhD Scholar, Mahatma Gandhi Ayurved College Hospital and Research centre, Wardha, MS 442001 Email: drrahulkgupta17@gmail.com to treat Cancer and rheumatism.(2) The juice of the leaves is used as a gargle for sore throat and the leaf paste for wounds of domestic animals.(3) The unripe fruits of M. annua found to have antioxidant activity(4) and the ash of fruits mixed with coconut oil are used to cure burns.(5) The roots are used as local sedative and antidote to scorpion stings.(6) Seed oil is used for abscesses and treating itching and skin infections
The present study revealed the in vitro antioxidant activities of ethanolic root extract partitioned in different solvents by scavenging effect on 1,1-diphenyl-2 -picryldrazyl, assay to protect the oxidative damage
Summary
Antioxidants play a significant role to protect harm caused by oxidative stress (OS). *Corresponding Author: Rahul Kumar Gupta, PhD Scholar, Mahatma Gandhi Ayurved College Hospital and Research centre, Wardha, MS 442001 Email: drrahulkgupta17@gmail.com to treat Cancer and rheumatism.(2) The juice of the leaves is used as a gargle for sore throat and the leaf paste for wounds of domestic animals.(3) The unripe fruits of M. annua found to have antioxidant activity(4) and the ash of fruits mixed with coconut oil are used to cure burns.(5) The roots are used as local sedative and antidote to scorpion stings.(6) Seed oil is used for abscesses and treating itching and skin infections. Free radicals are produced during oxidation which can be trapped by antioxidants. Natural exogenic antioxidant substances are available i.e. flavonoids, phenolic diterpenes, oils, vitamins phenolic acids and plant pigments like anthocyanins scavenge free radicals such as hydro peroxide, peroxide or lipid peroxidation.
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